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Showing posts with label Pharmacology and Toxicology. Show all posts

Showing posts with label Pharmacology and Toxicology. Show all posts

Tuesday, February 22, 2011

Animal Clinical Chemistry (A Practical Handbook)

Description

Animal Clinical Chemistry
CRC Press | April 1, 2009 | ISBN-10: 1420080113 | 368 pages | PDF | 1.94 MB

Newcomers to the animal clinical chemistry and toxicology fields quickly find that the same rules of human medicine do not always apply. Following in the footsteps of its standard-setting first edition, Animal Clinical Chemistry: A Practical Handbook for Toxicologists and Biomedical Researchers, Second Edition collates information widely dispersed in journals and book chapters, focusing on the most-relevant literature to experimental toxicology and its distinction from human medicine.

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Monday, January 17, 2011

Cyclic Gmp: Synthesis, Metabolism, and Function

This volume is dedicated to the topic of cyclic GMP. Chapters include discussions on the guanylyl cyclase and phosphodiesterase isoenzyme families for cyclic GMP synthesis and hydrolysis, cyclic GMP-dependent protein kinases, and various hormones and ligands that regulate cyclic GMP formation and/or metabolism. Several chapters also deal with some of the effects of cyclic GMP on other second messengers such as calcium ion transport and smooth muscle relaxation. Some clinical studies with cyclic GMP and atrial natriuretic peptide are also discussed. The last chapter raises many important questions in the field that remain to be addressed.

Key Features
* Isoforms of guanylyl cyclase and phosphodiesterase isoenzyme families for cyclic GMP synthesis and hydrolysis
* Cyclic GMP-dependent protein kinase
* Hormones and ligands that regulate GMP formation and/or metabolism
* Effects of cyclic GMP on other second messengers and some functions such as smooth muscle relaxation and ion transport
* Clinical studies with cyclic GMP and atrial natriuretic peptide
* Important questions and experiments for the future.

cGMP: Generators, Effectors and Therapeutic Implications

After the discovery of endogenous NO formation in the late '80s and the 1998 Nobel Prize in Physiology or Medicine, many researchers and physicians again became interested in the NO/sGC interaction and cGMP-dependent signaling. This book is an enthusiastic celebration of cyclic guanosine monophosphate (cGMP) and amply illustrates the importance of this field of science to patients and the way in which the field has evolved. It is exclusively devoted to this exciting and important signaling molecule, addressing all recent advances in understanding guanylate cyclase regulation, NO/sGC interactions, cGMP effector mechanisms and their pathophysiological and pharmacological implications. Particular attention will also be given to clinical applications of the novel cGMP-elevating drugs which are on the horizon, thus spanning the continuum from basic science to clinic.

Opioid Research: Methods and Protocols

Univ. of Texas MD Anderson Cancer Center, Houston. Text provides a comprehensive collection of methods and protocols used in current opioid research. Covers molecular and genetic techniques and behavioral analysis of animal models. Provides state-of-the-art techniques plus clinical applications. For researchers and practitioners.

Basic and Clinical Pharmacology, 10 th Edition (LANGE Basic Science)

The most trusted and up-to-date pharmacology text in medicine -- completely redesigned to make the learning process even more interesting and efficient

5 Star Doody's Review!
"This is the most widely used textbook for teaching pharmacology to health professionals. This 11th edition is far superior to any previous editions....The authors' goals are to provide a complete, authoritative, current, and readable textbook of pharmacology for students in health sciences. Testimony to their success is the widespread use of this work as required textbook for pharmacology courses around the world. This book is used extensively by thousands of medical, pharmacy, podiatry, nursing, and other health professions students to study pharmacology. Likewise, it remains a valuable resource for residents and practicing physicians....I continue to use this book as a required resource for all courses that I teach to medical, nursing, and allied health students. It is authoritative, readable, and supported by numerous learning tools."--Doody's Review Service

Organized to reflect the syllabi in Pharmacology courses, Basic & Clinical Pharmacology covers all the important concepts students need to know about the science of pharmacology and its application to clinical practice. It is acknowledged worldwide as the field’s most current, authoritative, and comprehensive textbook. To be as clinically relevant as possible, the book features a strong focus on the choice and use of drugs in patients and the monitoring of their effects.

Coverage that spans every important aspect of medical pharmacology:

Basic Principles
Autonomic Drugs
Cardiovascular-Renal Drugs
Drugs with Important Actions on Smooth Muscle
Drugs that Act in the Central Nervous System
Drugs Used to Treat Diseases of the Blood, Inflammation, and Gout
Endocrine Drugs
Chemotherapeutic Drugs
Toxicology

NEW to this edition:

Full-color presentation, including 300+ illustrations
Case studies introduce clinical problems in many chapters
Drug summary tables for key information in comparative context
Descriptions of important newly released drugs, including new immunopharmacologic agents
Expanded coverage of general concepts relating to newly discovered receptors, receptor mechanisms, and drug transporters

Goodman & Gilman's The Pharmacological Basis of Therapeutics

The undisputed leader in medical pharmacology, without equal. Updated to reflect all critical new developments in drug action and drug-disease interaction. This is the “desert island” book of all medical pharmacology—if you can own just one pharmacology book, this is it.

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Stockley's Drug Interactions, 8th Edition

First published over twenty years ago, "Stockley's Drug Interactions" is still the most indispensable and authoritative international source of drug interaction information. Based upon the many thousands of published clinical papers and reports, it provides a series of detailed yet concise monographs designed for quick and easy reference. Each monograph contains a summary, clinical evidence for the interaction under discussion, its probable mechanism, clinical importance and management. Individual interactions are assembled alphabetically into chapters, grouped therapeutically, pharmacologically or individually. Both Recommended International Nonproprietary Names (rINN) and US Adopted Names (USAN) are used throughout the book.

Stockley's Drug Interactions 2009 Pocket Companion

ISBN: 0853695040
Title: Stockley's Drug Interactions: A Source Book of Interactions, Their Mechanisms, Clinical Importance and Management
Author: Ivan H. Stockley
Publisher: Pharmaceutical Press
Publication Date: 2002-12
Number Of Pages: 1080

This new edition continues to provide the busy health care professional with a small and conveniently sized quick reference "Stockley" text. "Stockley's Drug Interactions Pocket Companion 2009" draws on the wealth of clinically evaluated, evidence-based information on drug-drug, drug-herb and drug-food interactions that is presented in the full reference work, "Stockley's Drug Interactions".

Stockley’s Drug Interactions Pocket Companion 2009 provides busy healthcare professionals with a small and conveniently sized, quick-reference Stockley text. It draws on the wealth of clinically evaluated, evidence-based information on drug-drug, drug-herb and drug-food interactions that is presented in the full reference work, Stockley’s Drug Interactions .: Follows the familiar format of the Stockley products; Includes over 1500 interaction monographs pertaining to specific drugs or drug groups; Arranged alphabetically for ease of searching; Contains a comprehensive index; Easy-to-use severity rating symbols offer guidance to the user on the clinical significance of the interaction; An essential clinical reference for physicians, pharmacists, nurses and other healthcare professionals. Due to the wide international appeal of this content, the text is now translated into Spanish, Italian and Japanese.

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Lactoferrin: Natural - Multifunctional - Antimicrobial

Lactoferrin is emerging as one of the effective natural antimicrobial intervention in food safety and preservation. Explored in-depth, Lactoferrin: Natural - Multifunctional - Antimicrobial provides you with an introduction to microbial blocking technology and explores its potential as a novel antimicrobial intervention in the multi-hurdle approach to food safety. This book consolidates the science and technological developments in the fast growing area of lactoferrin research.

Nanotechnology for Cancer Therapy

Encouraging communication between clinical investigators and nanoscientists, Nanotechnology for Cancer Therapy focuses specifically on effective and promising nanoscience and nanotechnology strategies for imaging and treating cancer. Among the various approaches considered, nanotechnology offers the best promise for the targeted delivery of drugs and genes to a tumor site and for alleviating side effects of chemotherapeutic agents. Renowned industrial and academic researchers describe the advantages of nanoparticles as sensing, delivery, image enhancement agents for cancer treatments, and various types of useful nanoparticles such as polymeric nanoparticles and dendrimers.

Sunday, January 9, 2011

Validation of Toxicogenomic Technologies

Toxicogenomics has been described as a discipline combining ex-pertise in toxicology, genetics, molecular biology, and environmental health to elucidate the response of living organisms to stressful environ-ments. It includes the study of how genomes respond to toxicant expo-sures and how genotype affects responses to toxicant exposures. As the technologies for monitoring these responses rapidly develop, it is critical that scientists and regulators are confident that the technologies are reliable and reproducible and that the data analyses have been validated. To discuss these issues in a public forum, the Committee on the Validation of Toxicogenomic Technologies designed a workshop to consider the current practice and advances in the validation of toxicogenomic tech-nologies. The workshop focused on the technical aspects of validation, recognizing it as a prerequisite for considering other important issues, such as biological validation (e.g., validating the use of microarray “sig-natures” to describe a toxic effect).

Drug Delivery Systems, Second Edition

Drug delivery technologies represent a vast and vital area of Research and Development. The demand for innovative drug delivery systems continues to grow, and this growth continues to drive new developments. Building on the foundation provided by the first edition, Drug Delivery Systems, Second Edition covers the latest developments in both industry and academia. New in this edition: · Chapter focusing on novel technologies and their global outlook · Coverage of electronically controlled drug delivery · Macrocapsules and nanoparticles in drug targeting · Drug nanocrystals and other new delivery systems · Updated information on liposomes as carriers Written in a straightforward, clear, and concise manner, the author provides a global perspective on current and future advances and market opportunities. Drug Delivery Systems, Second Edition answers the need for comprehensive information in a single resource for anyone venturing into this area of drug development.

Clarke's Analysis of Drugs and Poisons, Third Edition

This practical manual and standard reference work provides an authoritative source of analytical data for drugs and poisons. It is intended for use primarily by scientists faced with identifying and quantifying these substances in body fluids, tissue samples and pharmaceutical and industrial products. This completely revised and updated new edition now comprises two volumes housed in a handy slipcase. Clarke's Analysis of Drugs and Poisons is an essential requirement for all forensic and crime laboratories, toxicologists, clinical pharmacology departments, poison information centres, pathologists, clinical toxicologists, hospital pharmacists and analytical chemists. Clarke's Analysis of Drugs and Poisons was previously published as Clarke's Analysis and Identification of Drugs.

Color Atlas of Pharmacology, 3rd Edition

Updated with the most important new substances and scientific developments, the third edition of The Color Atlas of Pharmacology makes it easier than ever for students, nurses, and practicing physicians to keep up with the latest developments in this constantly changing field. Featuring a user-friendly layout, jargon-free language, and more than 160 spectacular color charts and illustrations, the atlas is divided in to four, color-coded sections:

Part 1 - General pharmacology - includes descriptions of substance formulation, absorption, distribution, elimination, and molecular mechanisms of action Part 2 - Systems pharmacology - with special emphasis on the functional and therapeutic aspects of a wide range of medicinal agents Part 3 - Therapy of selected diseases - such as osteoporosis, acute myocardial infarction, migraine, asthma, tropical diseases, and many more Part 4 - Drug Index - helpfully listed by substance, generic, and brand names

Concise, portable, and packed with information, the third edition of The Color Atlas of Pharmacology is the most practical first-stop reference for today's busy healthcare professional.

Goodman & Gilman's The Pharmacological Basis of Therapeutics

The undisputed leader in medical pharmacology, without equal. Updated to reflect all critical new developments in drug action and drug-disease interaction. This is the “desert island” book of all medical pharmacology—if you can own just one pharmacology book, this is it.

Drug Delivery Systems, Second Edition

Drug delivery technologies represent a vast and vital area of Research and Development. The demand for innovative drug delivery systems continues to grow, and this growth continues to drive new developments. Building on the foundation provided by the first edition, Drug Delivery Systems, Second Edition covers the latest developments in both industry and academia. New in this edition: · Chapter focusing on novel technologies and their global outlook · Coverage of electronically controlled drug delivery · Macrocapsules and nanoparticles in drug targeting · Drug nanocrystals and other new delivery systems · Updated information on liposomes as carriers Written in a straightforward, clear, and concise manner, the author provides a global perspective on current and future advances and market opportunities. Drug Delivery Systems, Second Edition answers the need for comprehensive information in a single resource for anyone venturing into this area of drug development.

Opioid Research: Methods and Protocols

Univ. of Texas MD Anderson Cancer Center, Houston. Text provides a comprehensive collection of methods and protocols used in current opioid research. Covers molecular and genetic techniques and behavioral analysis of animal models. Provides state-of-the-art techniques plus clinical applications. For researchers and practitioners.

cGMP: Generators, Effectors and Therapeutic Implications

After the discovery of endogenous NO formation in the late '80s and the 1998 Nobel Prize in Physiology or Medicine, many researchers and physicians again became interested in the NO/sGC interaction and cGMP-dependent signaling. This book is an enthusiastic celebration of cyclic guanosine monophosphate (cGMP) and amply illustrates the importance of this field of science to patients and the way in which the field has evolved. It is exclusively devoted to this exciting and important signaling molecule, addressing all recent advances in understanding guanylate cyclase regulation, NO/sGC interactions, cGMP effector mechanisms and their pathophysiological and pharmacological implications. Particular attention will also be given to clinical applications of the novel cGMP-elevating drugs which are on the horizon, thus spanning the continuum from basic science to clinic.

Medical Pharmacology at a Glance, 4th Edition

"Medical Pharmacology at a Glance" is one of the most renowned undergraduate texts in the field of medical pharmacology. Following on from the success of the previous three editions, Professor Michael Neal, one of the great teachers of medical pharmacology, has extensively revised and updated the fourth edition to take account of the rapid developments in the field. This incredibly useful book summarises the core principles of the mode of action of drugs and puts this information within the context of body systems and specific clinical problems. The author discusses the mechanisms of action of each drug, indicating the therapeutics of choice for specific conditions. "Medical Pharmacology at a Glance" follows the now familiar, easy-to-use double page spread format of the at a Glance series. Each section contains a clear illustration depicting the major drugs and their interaction within a particular body system and a concise account of the topic. Key features of the fourth edition include: new material on anti-platelet drugs in the cardiovascular section; new section on immunological drugs; new material on general anaesthetic and anti-viral drugs; and the use of Recommended International Non-proprietary Names (rINN) for drugs. "Medical Pharmacology at a Glance" is ideal for pharmacology revision and for use during clinical placements. It is an essential buy for medical students and scientists requiring a succinct and lucid account of medical pharmacology.

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